I too was very careful about what I put in my body with my first child...And he was born with Epstiens, ASD, and pulmonary stenosis...Doctors told me that there was nothing I did or they were aware of that caused this, but just a simple it happens...i am sure that smoking and caffiene use aren;t the best things for your fetus, but conception if the biggest mystery of life so is the complete effects of these substances. One woman might experience nothing while another will.